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23 days ago

A design approach for bitopic kinase inhibitors

SIGNALSMONITORTECHNOLOGY

What's happening

SignalsMonitor is following this as a technology story. Nature is the outlet attached so far. The first report grouped here was at 23 Sept 2026, 16:00 UTC. The headline in use is “A design approach for bitopic kinase inhibitors”. This note is SignalsMonitor's own briefing, not the publisher's article.

What we know

Nature, Published online: 23 September 2026; doi:10. 1038/s41586-026-11056-8 Detailed analyses of ligand choice, linkage vector and linker length enabled the development of bitopic inhibitors of ABL1 and EGFR kinases, including an ABL1 inhibitor with enhanced activity against resistance mutations and reduced off-target toxicity.

NatureRead at Nature

Story timeline

Reports grouped into this story, earliest first. Exact repeats from the same outlet are collapsed.

Reported by 1 outlet

  • Nature