24 days ago
Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila
What's happening
SignalsMonitor is following this as a technology story. Nature is the outlet attached so far. The first report grouped here was at 23 Sept 2026, 16:00 UTC. 2 material updates are listed in the timeline. The headline in use is “Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila”. This note is SignalsMonitor's own briefing, not the publisher's article.
What we know
Nature, Published online: 23 September 2026; doi:10. 1038/s41586-026-11029-x In Drosophila, the protein Lsp2, which is induced by dietary essential amino acids, is a key physiological effector of mTORC1, and mutant flies that lack the Lsp2 gene exhibit reduced translation of TOP mRNAs and improved longevity.
Story timeline
Reports grouped into this story, earliest first. Exact repeats from the same outlet are collapsed.
- First reported by Nature
Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila
- Picked up by Nature
Lsp2 links early-life diet to adult translation and lifespan in Drosophila
Reported by 1 outlet
- Nature